{"id":48,"date":"2016-11-06T14:41:52","date_gmt":"2016-11-06T20:41:52","guid":{"rendered":"https:\/\/eportfolios.isucomm.iastate.edu\/omer\/?p=48"},"modified":"2016-11-07T20:57:47","modified_gmt":"2016-11-08T02:57:47","slug":"48","status":"publish","type":"post","link":"https:\/\/eportfolios.isucomm.iastate.edu\/omer\/2016\/11\/06\/48\/","title":{"rendered":"Sugar is Sugar"},"content":{"rendered":"<p>Considering that our cells depend on sugar for energy, it makes sense that we evolved an innate love for sweetness.<\/p>\n<p>Often regarded as \u2018white poison\u2019, sugar has attracted huge criticism from both scientists and nutritionists for its negative effects on a body&#8217;s health. More people are starting to realize\u00a0that sugar is the key reason behind the obesity epidemic. This epidemic is shown by a <a href=\"http:\/\/www.who.int\/mediacentre\/factsheets\/fs311\/en\/\">World Health Organization<\/a>\u00a0report, stating obesity rates have doubled since 1980.<\/p>\n<p>The argument that sugar is a toxin depends on some technical details about the different ways the human body gets energy from different types of sugar. Today, Americans eat most of their sugar in two main forms: table sugar and high-fructose corn syrup.<\/p>\n<p>Refined sucrose is commonly referred to as\u00a0table sugar\u00a0or just\u00a0sugar. Sucrose\u00a0plays a central role as a leading processed food additive. A bond between one glucose molecule and one fructose molecule makes a sucrose molecule.<\/p>\n<div style=\"width: 455px\" class=\"wp-caption alignnone\"><a href=\"https:\/\/explorebiochemistryworld.wordpress.com\/category\/uncategorized\/page\/3\/\"><img loading=\"lazy\" decoding=\"async\" class=\"\" src=\"http:\/\/www.nutrientsreview.com\/wp-content\/uploads\/2014\/09\/Sucrose.jpg\" alt=\"Fig 1. \" width=\"445\" height=\"294\" \/><\/a><p class=\"wp-caption-text\"><a href=\"https:\/\/explorebiochemistryworld.wordpress.com\/category\/uncategorized\/page\/3\/\">Fig 1.<\/a>\u00a0Dehydration of a glucose and fructose molecule to form a sucrose, a disaccharide.<\/p><\/div>\n<p>Another industrial sugar that is prevalent in our food supply is fructose.\u00a0High fructose corn syrup\u00a0(HFCS)\u00a0is a sweetener made from\u00a0corn starch\u00a0that has been\u00a0processed\u00a0by\u00a0glucose isomerase\u00a0to convert some of its\u00a0glucose\u00a0into\u00a0fructose.<\/p>\n<div style=\"width: 530px\" class=\"wp-caption alignnone\"><a href=\"http:\/\/imgur.com\/gallery\/Fill6\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium\" src=\"http:\/\/i.imgur.com\/6rAkEud.gif\" alt=\"Fig 2.\" width=\"520\" height=\"194\" \/><\/a><p class=\"wp-caption-text\"><a href=\"http:\/\/imgur.com\/gallery\/Fill6\">Fig 2.<\/a>\u00a0Glucose isomerase converting glucose to fructose. On average HFCS is 15-20% higher in fructose content.<\/p><\/div>\n<p>These sugars have no nutritional value, and are primarily used in the food processing industry to increase the shelf-life of baked products and for improving the color, texture and flavor of food and beverages.<\/p>\n<p>Despite the type of sugar consumed, cells in the body\u00a0are interested in dealing with monosaccharides, fructose and glucose, not the bulkier disaccharides compounds, such as sucrose.\u00a0Enzymes in the small intestine produce the sucrase enzyme to assist in the hydrolysis process that cleaves sucrose into fructose and glucose rapidly.<\/p>\n<p>Glucose travels through the bloodstream to all of our tissues and is able to be readily utilized as a source of energy\u00a0by\u00a0every cell. However when investigating the metabolism of fructose, we observe that liver cells are one of few that can convert fructose to energy, this burden of metabolizing fructose becomes a task assigned to entirely one organ. The liver completes\u00a0this task primarily by turning fructose into glucose and lactate.<\/p>\n<p>Processing large amounts of fructose tolls the liver, for the reason that it spends so much energy turning fructose into other molecules that it may not have much energy left for all its other functions, such as converting\u00a0stored sugar to functional sugar when the body\u2019s sugar (glucose) levels fall below normal. A consequence of this energy depletion is <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19151107\">production of uric acid<\/a>, <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19151107\">which research has linked to gout, kidney stones and high blood pressure.<\/a><\/p>\n<p>&nbsp;<\/p>\n<div style=\"width: 248px\" class=\"wp-caption alignleft\"><a href=\"http:\/\/biology-igcse.weebly.com\/uploads\/1\/5\/0\/7\/15070316\/9767305_orig.gif\"><img loading=\"lazy\" decoding=\"async\" class=\"\" src=\"http:\/\/biology-igcse.weebly.com\/uploads\/1\/5\/0\/7\/15070316\/9767305_orig.gif\" alt=\"Fig 3.\" width=\"238\" height=\"357\" \/><\/a><p class=\"wp-caption-text\"><a href=\"http:\/\/biology-igcse.weebly.com\/uploads\/1\/5\/0\/7\/15070316\/9767305_orig.gif\">Fig 3.<\/a> The control of blood glucose levels.<\/p><\/div>\n<p>The control\u00a0of blood glucose\u00a0levels is carried out by the pancreas and the liver. Insulin and glucagon\u00a0hormones are secreted by the\u00a0pancreas\u00a0and are transported to the\u00a0liver through the bloodstream. When glucose levels are low, stored glycogen is broken down to glucose, which is released into the bloodstream. When there is excess glucose in the blood stream, glucose stimulates the pancreas to secrete the hormone insulin. Insulin converts excess glucose in the\u00a0blood into glycogen. Insulin has been shown to <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/10751202\">boost production<\/a> of the hormone leptin, which suppresses hunger.<\/p>\n<p>Fructose does not trigger insulin production and appears to <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4429636\/\">raise levels of the hormone grehlin<\/a>, which keeps us hungry.<\/p>\n<p>In studies\u00a0by Kimber Stanhope of the University of California Davis and other researchers, excess fructose consumption\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15983189\">increased fat production<\/a>, especially <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19381015\">in the liver<\/a>, and raised levels of circulating triglycerides, which are a risk factor for <a href=\"http:\/\/www.stltoday.com\/lifestyles\/health-med-fit\/health\/to-your-good-health\/dr-donohue-triglycerides-as-well-as-cholesterol-clog-arteries\/article_188853eb-ac08-5a59-9eeb-4e235aaaec07.html\">clogged arteries and cardiovascular disease<\/a>.<\/p>\n<p>So given this information what should we conclude about our consumption of sugar? Is one sugar better than the other.<\/p>\n<p>Some nutritionists and doctors have the thought that &#8220;sugar is sugar&#8221;.\u00a0Since it\u2019s all converted into glucose anyway, they would say it doesn\u2019t really matter. They would also argue that\u00a0what matters far more than the type of sugar is simply reducing the\u00a0overall sugar consumption and caloric intake.<\/p>\n<p>I believe within the next few years as more conclusive studies shed light on the different forms of sugars and their relative effect on the human body, the catchphrase &#8220;sugar is sugar&#8221; will evolve\u00a0to become more specific.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Considering that our cells depend on sugar for energy, it makes sense that we evolved an innate love for sweetness. Often regarded as \u2018white poison\u2019, sugar has attracted huge criticism from both scientists and nutritionists for its negative effects on a body&#8217;s health. More people are starting to realize\u00a0that sugar is the key reason behind&#8230; <\/p>\n<p><a class=\"moretag\" href=\"https:\/\/eportfolios.isucomm.iastate.edu\/omer\/2016\/11\/06\/48\/\">Read more<\/a><\/p>\n","protected":false},"author":4518,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-48","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/eportfolios.isucomm.iastate.edu\/omer\/wp-json\/wp\/v2\/posts\/48","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/eportfolios.isucomm.iastate.edu\/omer\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/eportfolios.isucomm.iastate.edu\/omer\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/eportfolios.isucomm.iastate.edu\/omer\/wp-json\/wp\/v2\/users\/4518"}],"replies":[{"embeddable":true,"href":"https:\/\/eportfolios.isucomm.iastate.edu\/omer\/wp-json\/wp\/v2\/comments?post=48"}],"version-history":[{"count":8,"href":"https:\/\/eportfolios.isucomm.iastate.edu\/omer\/wp-json\/wp\/v2\/posts\/48\/revisions"}],"predecessor-version":[{"id":61,"href":"https:\/\/eportfolios.isucomm.iastate.edu\/omer\/wp-json\/wp\/v2\/posts\/48\/revisions\/61"}],"wp:attachment":[{"href":"https:\/\/eportfolios.isucomm.iastate.edu\/omer\/wp-json\/wp\/v2\/media?parent=48"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/eportfolios.isucomm.iastate.edu\/omer\/wp-json\/wp\/v2\/categories?post=48"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/eportfolios.isucomm.iastate.edu\/omer\/wp-json\/wp\/v2\/tags?post=48"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}