Microbes are microorganisms that human can’t see it without the aid of microscopes. As small as it can be, some microbes: bacteria, viruses,fungi, and parasites have the wide range of ability to cause harm to human, animals and environment. There was no cure to bacterial associated diseases or infections until the discovery of the first ever antibiotic, penicillin by Alexander Fleming in 1928. Since then, antibiotics have been a life saving drugs for people. However, many factors such as over prescription of the antibiotics, incorrect usage of antibiotics and genetic mutation of microbes have given rise to the antibiotic resistance. The image below from Centers for Disease Control and Prevention below provide the spread of antibiotic resistance.
Image available from: https://www.cdc.gov/drugresistance/about.html